| Date | Location | Result | |
| Nov 20, 2010 | Murray, Ky. | Murray State 28, Tennessee State 23 | Box score |
| Nov 13, 2010 | Martin, Tenn. | UT Martin 37, Tennessee State 0 | Box score |
| Nov 06, 2010 | Nashville, TN | Eastern Illinois 31, Tennessee State 28 | Box score |
| Oct 23, 2010 | Nashville, TN | Tennessee Tech 21, Tennessee State 10 | Box score |
| Oct 16, 2010 | Jacksonville, Ala. | Jacksonville State 24, Tennessee State 0 | Box score |
| Oct. 9, 2010 | Cape Girardeau, Mo. | Southeast Missouri 19, Tennessee State 17 | Box score |
| Oct. 2, 2010 | Indianapolis, Ind. | Tennessee State 37, North Carolina A&T 7 | Box score |
| Sep 25, 2010 | Atlanta, GA | Tennessee State 29, Florida A&M 18 | Box score |
| Sep 18, 2010 | Nashville, TN | Austin Peay 26, Tennessee State 23 | Box score |
| Sep 11, 2010 | Memphis, TN | Jackson State 33, Tennessee State 26 | Box score |
| Sep 04, 2010 | Nashville, TN | Tennessee State 27, Alabama A&M 14 | Box score |